Statins and fenofibrate affect skeletal muscle chloride conductance in rats by differently impairing ClC-1 channel regulation and expression

BACKGROUND AND PURPOSE: Statins and fibrates can produce mild to life-threatening skeletal muscle damage. Resting chloride channel conductance (gCl), carried by the ClC-1 channel, is reduced in muscles of rats chronically treated with fluvastatin, atorvastatin or fenofibrate, along with increased re...

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Detalhes bibliográficos
Main Authors: Pierno, S, Camerino, GM, Cippone, V, Rolland, J-F, Desaphy, J-F, De Luca, A, Liantonio, A, Bianco, G, Kunic, JD, George, AL, Camerino, D Conte
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers With Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697730/
https://ncbi.nlm.nih.gov/pubmed/19220292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00079.x
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