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Positive allosteric modulation of the human cannabinoid (CB(1)) receptor by RTI-371, a selective inhibitor of the dopamine transporter

BACKGROUND AND PURPOSE: In our search for an indirect dopamine agonist as therapy for cocaine addiction, several selective inhibitors of the dopamine transporter (DAT), which are 3-phenyltropane analogues, were assayed for their effect on locomotor activity in mice. Interestingly, several of the com...

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Détails bibliographiques
Auteurs principaux: Navarro, Hernán A, Howard, James L, Pollard, Gerald T, Carroll, F Ivy
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697692/
https://ncbi.nlm.nih.gov/pubmed/19226282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00124.x
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