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Shadows across μ-Star? Constitutively active μ-opioid receptors revisited

Constitutively active μ-opioid receptors (μ* receptors) are reported to be formed following prolonged agonist treatment of cells or whole animals. μ* receptors signal in the absence of activating ligand and a blockade of μ* activation of G-proteins by naloxone and naltrexone has been suggested to un...

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Bibliographic Details
Main Author: Connor, Mark
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697690/
https://ncbi.nlm.nih.gov/pubmed/19368530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00067.x
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