Thyroid hormone β receptor activation has additive cholesterol lowering activity in combination with atorvastatin in rabbits, dogs and monkeys

BACKGROUND AND PURPOSE: Thyroid hormone receptor (TR) agonists are in clinical trials for the treatment of hypercholesterolaemia. As statins are the standard of clinical care, any new therapies must have adjunctive activity, when given in combination with statins. As already known for the statins, t...

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Main Authors: Ito, BR, Zhang, B-H, Cable, EE, Song, X, Fujitaki, JM, MacKenna, DA, Wilker, CE, Chi, B, van Poelje, PD, Linemeyer, DL, Erion, MD
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697679/
https://ncbi.nlm.nih.gov/pubmed/19183199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00038.x
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