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C3a Receptor Deficiency Accelerates the Onset of Renal Injury in the MRL/lpr Mouse
The development and progression of systemic lupus erythematosus (SLE) is strongly associated with complement activation and deposition. The anaphylatoxin C3a is a product of complement activation with immunomodulatory properties, and the receptor for C3a (C3aR) is not only expressed by granulocytes...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697606/ https://ncbi.nlm.nih.gov/pubmed/19167760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.12.004 |
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