High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

Rapid imaging by antitumor antibodies has been limited by the prolonged targeting kinetics and clearance of labeled whole antibodies. Genetically engineered fragments with rapid access and high retention in tumor tissue combined with rapid blood clearance are suitable for labeling with short-lived r...

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Main Authors: Wu, Anna M., Yazaki, Paul J., Tsai, Shih-wa, Nguyen, Khoi, Anderson, Anne-Line, McCarthy, Deborah W., Welch, Michael J., Shively, John E., Williams, Lawrence E., Raubitschek, Andrew A., Wong, Jeffrey Y. C., Toyokuni, Tatsushi, Phelps, Michael E., Gambhir, Sanjiv S.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2000
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC26976/
https://ncbi.nlm.nih.gov/pubmed/10880576
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