High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

Rapid imaging by antitumor antibodies has been limited by the prolonged targeting kinetics and clearance of labeled whole antibodies. Genetically engineered fragments with rapid access and high retention in tumor tissue combined with rapid blood clearance are suitable for labeling with short-lived r...

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Detalhes bibliográficos
Main Authors: Wu, Anna M., Yazaki, Paul J., Tsai, Shih-wa, Nguyen, Khoi, Anderson, Anne-Line, McCarthy, Deborah W., Welch, Michael J., Shively, John E., Williams, Lawrence E., Raubitschek, Andrew A., Wong, Jeffrey Y. C., Toyokuni, Tatsushi, Phelps, Michael E., Gambhir, Sanjiv S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26976/
https://ncbi.nlm.nih.gov/pubmed/10880576
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