Wordt geladen...

IKKβ-mediated NF-κB Activation Attenuates Smac Mimetic-induced Apoptosis in Cancer Cells

Smac mimetics (SM) have been recently reported to kill cancer cells through the extrinsic apoptosis pathway mediated by autocrine tumor necrosis factor (TNF). SM also activates nuclear factor κB (NF-κB). However, how SM induces NF-κB and the role of NF-κB in SM-induced cancer cell death has not been...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Bai, Lang, Chen, Wenshu, Chen, Wenjie, Wang, Xia, Tang, Hong, Lin, Yong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697389/
https://ncbi.nlm.nih.gov/pubmed/19509265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0068
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!