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Correcting for bias in estimation of quantitative trait loci effects

Estimates of quantitative trait loci (QTL) effects derived from complete genome scans are biased, if no assumptions are made about the distribution of QTL effects. Bias should be reduced if estimates are derived by maximum likelihood, with the QTL effects sampled from a known distribution. The param...

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Hlavní autoři: Weller, Joel Ira, Shlezinger, Meital, Ron, Micha
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697222/
https://ncbi.nlm.nih.gov/pubmed/16093012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-37-6-501
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