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Correcting for bias in estimation of quantitative trait loci effects

Estimates of quantitative trait loci (QTL) effects derived from complete genome scans are biased, if no assumptions are made about the distribution of QTL effects. Bias should be reduced if estimates are derived by maximum likelihood, with the QTL effects sampled from a known distribution. The param...

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Detalhes bibliográficos
Main Authors: Weller, Joel Ira, Shlezinger, Meital, Ron, Micha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697222/
https://ncbi.nlm.nih.gov/pubmed/16093012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-37-6-501
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