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E2f6 and Bmi1 cooperate in axial skeletal development

Bmi1 is a Polycomb Group protein that functions as a component of Polycomb Repressive Complex 1 (PRC1) to control axial skeleton development through Hox gene repression. Bmi1 also represses transcription of the Ink4a-Arf locus and is consequently required to maintain the proliferative and self-renew...

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Hlavní autoři: Courel, Maria, Friesenhahn, Laurie, Lees, Jacqueline A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697036/
https://ncbi.nlm.nih.gov/pubmed/18366140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21516
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