Proapoptotic Effects of Dietary (n-3) Fatty Acids Are Enhanced in Colonocytes of Manganese-Dependent Superoxide Dismutase Knockout Mice

We recently demonstrated that (n-3) PUFA trigger the induction of apoptosis in the colon by enhancing phospholipid oxidation and mitochondrial Ca(2+) accumulation. To further elucidate the mechanisms regulating oxidative stress-induced apoptosis in vivo, a 2 × 2 experiment was designed using both wi...

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Détails bibliographiques
Auteurs principaux: Fan, Yang-Yi, Zhan, Yang, Aukema, Harold M., Davidson, Laurie A., Zhou, Lan, Callaway, Evelyn, Tian, Yanan, Weeks, Brad R., Lupton, Joanne R., Toyokuni, Shinya, Chapkin, Robert S.
Format: Artigo
Langue:Inglês
Publié: American Society for Nutrition 2009
Sujets:
Nutrition and Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696987/
https://ncbi.nlm.nih.gov/pubmed/19458032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.109.106203
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