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Chronic Estradiol Replacement to Aged Female Rats Reduces Anxiety-like and Depression-like Behavior and Enhances Cognitive Performance

Decline in the ovarian steroid, estradiol (E(2)), with the menopause transition may influence cognitive and affective processing of older women and there is evidence that hormone replacement therapies (HRTs) with E(2)-mimetics may provide benefit in some, but not all, women. The parameters that play...

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Bibliographic Details
Main Authors: Walf, Alicia A., Paris, Jason J., Frye, Cheryl A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696690/
https://ncbi.nlm.nih.gov/pubmed/19216030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2009.01.004
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