Llwytho...

p66Shc, oxidative stress and aging: Importing a lifespan determinant into mitochondria

The 66 KDa isoform of Shc and its signalling properties have attracted in the past years major interest in aging research. Here, we summarize p66Shc functions and outline a specific signalling route leading to mitochondrial import, that accounts for its pro-apoptotic activity upon oxidative stress....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pinton, Paolo, Rizzuto, Rosario
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696632/
https://ncbi.nlm.nih.gov/pubmed/18235239
Tagiau: Ychwanegu Tag
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