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Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies

Angiogenesis, a key process for the growth of human cancers, has recently been exploited for the development of a novel class of cancer therapeutics that was thought to have wide applications and not to induce resistance in the clinical setting. Indeed, anti-angiogenic therapy has become an importan...

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Autors principals: Rapisarda, Annamaria, Melillo, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696589/
https://ncbi.nlm.nih.gov/pubmed/19394890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2009.03.002
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