An improved method for genome wide DNA methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines

BACKGROUND: DNA methylation is a widely studied epigenetic mechanism known to correlate with gene repression and genomic stability. Development of sensitive methods for global detection of DNA methylation events is of particular importance. RESULTS: We here describe a technique, called modified meth...

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Main Authors: Li, Jian, Gao, Fei, Li, Ning, Li, Shengting, Yin, Guangliang, Tian, Geng, Jia, Shangang, Wang, Kai, Zhang, Xiuqing, Yang, Huanming, Nielsen, Anders Lade, Bolund, Lars
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696471/
https://ncbi.nlm.nih.gov/pubmed/19439076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-223
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