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Transcriptional Regulation of Th17 Cell Differentiation

The paradigm of effector T helper cell differentiation into either Th1 or Th2 lineages has been profoundly shaken by the discovery of T cells that secrete IL-17 and other inflammatory cytokines. This subset, referred to as Th17, is centrally involved in autoimmune disease and is important in host de...

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Autors principals: Ivanov, Ivaylo I., Zhou, Liang, Littman, Dan R.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696342/
https://ncbi.nlm.nih.gov/pubmed/18053739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2007.10.011
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