Effect of the Methoxychlor Metabolite HPTE on the Rat Ovarian Granulosa Cell Transcriptome In Vitro

Ovarian granulosa cells play a central role in steroidogenesis, which is critical for female reproduction. Follicle-stimulating hormone (FSH) promotes cyclic adenosine monophosphate (cAMP)-mediated signaling to regulate granulosa cell steroidogenesis. We have shown previously that 2,2-bis-(p-hydroxy...

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Hlavní autoři: Harvey, Craig N., Esmail, Mahmoud, Wang, Qi, Brooks, Andrew I., Zachow, Rob, Uzumcu, Mehmet
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Endocrine Toxicology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696328/
https://ncbi.nlm.nih.gov/pubmed/19414516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp089
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