Locus control region mediated regulation of adult β-globin gene expression

Many genes residing in gene clusters and expressed in a differentiation or developmental-stage specific manner are regulated by locus control regions (LCRs). These complex genetic regulatory elements are often composed of several DNAse I hypersensitive sites (HS sites) that function together to regu...

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Bibliographic Details
Main Authors: Liang, Shermi, Moghimi, Babak, Yang, Thomas P., Strouboulis, John, Bungert, Jörg
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696286/
https://ncbi.nlm.nih.gov/pubmed/18500726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21820
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