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Locus control region mediated regulation of adult β-globin gene expression
Many genes residing in gene clusters and expressed in a differentiation or developmental-stage specific manner are regulated by locus control regions (LCRs). These complex genetic regulatory elements are often composed of several DNAse I hypersensitive sites (HS sites) that function together to regu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696286/ https://ncbi.nlm.nih.gov/pubmed/18500726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21820 |
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