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HIV-1 Protease Dimer Interface Mutations that Compensate for Viral Reverse Transcriptase Instability in Infectious Virions
Mature enzymes encoded within the human immunodeficiency virus type 1 (HIV-1) genome [protease (PR), reverse transcriptase (RT) and integrase (IN)] derive from proteolytic processing of a large polyprotein (Gag-Pol). Gag-Pol processing is catalyzed by the viral PR, which is active as a homodimer. Th...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2007
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696282/ https://ncbi.nlm.nih.gov/pubmed/17651754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.06.073 |
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