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Zap-70 positive chronic lymphocytic leukemia co-existing with Jak 2 V671F positive essential thrombocythemia: A common defective stem cell?

Essential thrombocythemia (ET) co-existing with chronic lymphocytic leukemia (CLL) is extremely rare. We report two cases of ET with Jak 2 V617F in Zap-70+ CLL. ET is a myeloproliferative stem cell disease. Zap-70 expression in CLL correlates with non-mutated immunoglobulin genes. The occurrence of...

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Bibliografiske detaljer
Main Authors: Tabaczewski, Piotr, Nadesan, Sushani, Lim, Seah H
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695994/
https://ncbi.nlm.nih.gov/pubmed/18849073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2008.09.002
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