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Endothelin-1 Regulates Astrocyte Proliferation and Reactive Gliosis via a JNK/c-Jun Signaling Pathway

Reactive gliosis is characterized by enhanced glial fibrillary acidic protein (GFAP) expression, cellular hypertrophy, and astrocyte proliferation. The cellular and molecular mechanisms underlying this process are still largely undefined. We investigated the role of endothelin-1 (ET-1) in reactive g...

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Detalhes bibliográficos
Main Authors: Gadea, Ana, Schinelli, Sergio, Gallo, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695974/
https://ncbi.nlm.nih.gov/pubmed/18322086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5652-07.2008
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