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Site-Specific Integration of Retroviral DNA in Human Cells Using Fusion Proteins Consisting of Human Immunodeficiency Virus Type 1 Integrase and the Designed Polydactyl Zinc-Finger Protein E2C
During the life cycle of retroviruses, establishment of a productive infection requires stable joining of a DNA copy of the viral RNA genome into host cell chromosomes. Retroviruses are thus promising vectors for the efficient and stable delivery of genes in therapeutic protocols. Integration of ret...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695809/ https://ncbi.nlm.nih.gov/pubmed/19186211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.01.001 |
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