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The Ski protein can inhibit ligand induced RARα and HDAC3 degradation in the Retinoic acid signaling pathway

Recent data has implicated the Ski protein as being a physiologically relevant negative regulator of signaling by Retinoic Acid (RA). The mechanism by which Ski represses RA signaling is unknown. Co-immunoprecipitation and immunofluorescence assay showed that Ski and RARα are in the same complex in...

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Bibliographic Details
Main Authors: Zhao, Hongling, Ueki, Nobuhide, Marcelain, Katherine, Hayman, Michael J.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695671/
https://ncbi.nlm.nih.gov/pubmed/19341714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.141
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