In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from non-tumorigenic astrocytes and brain tumours

The mitochondrial lipidome influences ETC (electron transport chain) and cellular bioenergetic efficiency. Brain tumours are largely dependent on glycolysis for energy due to defects in mitochondria and oxidative phosphorylation. In the present study, we used shotgun lipidomics to compare the lipido...

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Hauptverfasser: Kiebish, Michael A, Han, Xianlin, Cheng, Hua, Seyfried, Thomas N
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Neurochemistry 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695587/
https://ncbi.nlm.nih.gov/pubmed/19570033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20090011
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