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Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer

Otto Warburg first proposed that cancer originated from irreversible injury to mitochondrial respiration, but the structural basis for this injury has remained elusive. Cardiolipin (CL) is a complex phospholipid found almost exclusively in the inner mitochondrial membrane and is intimately involved...

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Bibliografski detalji
Glavni autori: Kiebish, Michael A., Han, Xianlin, Cheng, Hua, Chuang, Jeffrey H., Seyfried, Thomas N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582368/
https://ncbi.nlm.nih.gov/pubmed/18703489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800319-JLR200
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