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Modeling of solvent-dependent conformational transitions in Burkholderia cepacia lipase

BACKGROUND: The characteristic of most lipases is the interfacial activation at a lipid interface or in non-polar solvents. Interfacial activation is linked to a large conformational change of a lid, from a closed to an open conformation which makes the active site accessible for substrates. While f...

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Autors principals: Trodler, Peter, Schmid, Rolf D, Pleiss, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695465/
https://ncbi.nlm.nih.gov/pubmed/19476626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-9-38
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