Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein

BACKGROUND: Defects in the human Shwachman-Bodian-Diamond syndrome (SBDS) protein-coding gene lead to the autosomal recessive disorder characterised by bone marrow dysfunction, exocrine pancreatic insufficiency and skeletal abnormalities. This protein is highly conserved in eukaryotes and archaea bu...

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Autors principals: Ng, C Leong, Waterman, David G, Koonin, Eugene V, Walters, Alison D, Chong, James PJ, Isupov, Michail N, Lebedev, Andrey A, Bunka, David HJ, Stockley, Peter G, Ortiz-Lombardía, Miguel, Antson, Alfred A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695463/
https://ncbi.nlm.nih.gov/pubmed/19454024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-9-32
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