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Role of Shwachman-Bodian-Diamond syndrome protein in translation machinery and cell chemotaxis: a comparative genomics approach
Shwachman-Bodian-Diamond syndrome (SBDS) is linked to a mutation in a single gene. The SBDS proinvolved in RNA metabolism and ribosome-associated functions, but SBDS mutation is primarily linked to a defect in polymorphonuclear leukocytes unable to orient correctly in a spatial gradient of chemoattr...
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| Format: | Artigo |
| Jezik: | Inglês |
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Dove Medical Press
2011
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202468/ https://ncbi.nlm.nih.gov/pubmed/22046100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/AABC.S23510 |
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