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How are T(H)1 and T(H)2 effector cells made?

Differentiation of T(H)1 and T(H)2-effector cells proceeds through several phases: First, naïve CD4(+) precursor cells are instructed to differentiate as appropriate to optimally fight the infectious threat encountered. This process is governed by the IL12 and IL4 cytokines, as well as by signaling...

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Detalhes bibliográficos
Main Authors: Amsen, Derk, Spilianakis, Charalampos G., Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695256/
https://ncbi.nlm.nih.gov/pubmed/19375293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.03.010
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