Disruption of the neurexin 1 gene is associated with schizophrenia

Deletions within the neurexin 1 gene (NRXN1; 2p16.3) are associated with autism and have also been reported in two families with schizophrenia. We examined NRXN1, and the closely related NRXN2 and NRXN3 genes, for copy number variants (CNVs) in 2977 schizophrenia patients and 33 746 controls from se...

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Detalhes bibliográficos
Main Authors: Rujescu, Dan, Ingason, Andres, Cichon, Sven, Pietiläinen, Olli P.H., Barnes, Michael R., Toulopoulou, Timothea, Picchioni, Marco, Vassos, Evangelos, Ettinger, Ulrich, Bramon, Elvira, Murray, Robin, Ruggeri, Mirella, Tosato, Sarah, Bonetto, Chiara, Steinberg, Stacy, Sigurdsson, Engilbert, Sigmundsson, Thordur, Petursson, Hannes, Gylfason, Arnaldur, Olason, Pall I., Hardarsson, Gudmundur, Jonsdottir, Gudrun A., Gustafsson, Omar, Fossdal, Ragnheidur, Giegling, Ina, Möller, Hans-Jürgen, Hartmann, Annette M., Hoffmann, Per, Crombie, Caroline, Fraser, Gillian, Walker, Nicholas, Lonnqvist, Jouko, Suvisaari, Jaana, Tuulio-Henriksson, Annamari, Djurovic, Srdjan, Melle, Ingrid, Andreassen, Ole A., Hansen, Thomas, Werge, Thomas, Kiemeney, Lambertus A., Franke, Barbara, Veltman, Joris, Buizer-Voskamp, Jacobine E., Sabatti, Chiara, Ophoff, Roel A., Rietschel, Marcella, Nöthen, Markus M., Stefansson, Kari, Peltonen, Leena, Clair, David St, Stefansson, Hreinn, Collier, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695245/
https://ncbi.nlm.nih.gov/pubmed/18945720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn351
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