Protective effect of the AT(137)RQ and ARQK(176) PrP alleles against classical scrapie in Sarda breed sheep

The susceptibility of sheep to scrapie is under the control of the host’s prion protein (PrP) gene and is also influenced by the strain of the agent. PrP polymorphisms at codons 136 (A/V), 154 (R/H) and 171 (Q/R/H) are the main determinants of susceptibility/resistance of sheep to classical scrapie....

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Autors principals: Vaccari, Gabriele, Scavia, Gaia, Sala, Marcello, Cosseddu, Gianmario, Chiappini, Barbara, Conte, Michela, Esposito, Elena, Lorenzetti, Raniero, Perfetti, Gabriella, Marconi, Paola, Scholl, Francesco, Barbaro, Katia, Bella, Antonino, Nonno, Romolo, Agrimi, Umberto
Format: Artigo
Idioma:Inglês
Publicat: EDP Sciences 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695041/
https://ncbi.nlm.nih.gov/pubmed/19171116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/vetres/2009002
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