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TGF-β has paradoxical and context dependent effects on proliferation and anoikis in human colorectal cancer cell lines
TGF-β is a pluripotent cytokine that can have both tumor suppressing and tumor promoting effects on epithelial cells. It is unclear what determines when TGF-β and its signaling pathway act predominantly as a tumor suppressor pathway or as a tumor-promoter pathway and whether TGF-β can have both clas...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694855/ https://ncbi.nlm.nih.gov/pubmed/18651288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08977190802291667 |
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