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Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility

One potential physiological target for new antischistosomals is the parasite’s system for excretion of wastes and xenobiotics. P-glycoprotein (Pgp), a member of the ATP-binding cassette superfamily of proteins, is an ATP-dependent efflux pump involved in transport of toxins and xenobiotics from cell...

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Detaylı Bibliyografya
Asıl Yazarlar: Messerli, Shanta M., Kasinathan, Ravi S., Morgan, William, Spranger, Stefani, Greenberg, Robert M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694853/
https://ncbi.nlm.nih.gov/pubmed/19406169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2009.04.007
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