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No evidence of BRCA2 mutations in chromosome 13q-linked Utah high-risk prostate cancer pedigrees

BACKGROUND: Germline mutations in the BRCA2 gene have been suggested to account for about 5% of familial prostate cancer; mutations have been reported in 2% of early onset (i.e., ≤ 55 years) prostate cancer cases and a segregating founder mutation has been identified in Iceland (999del5). However, t...

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Hlavní autoři: Allen-Brady, Kristina, Farnham, James M, Camp, Nicola J, Karlins, Eric, Ostrander, Elaine A, Cannon-Albright, Lisa A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694822/
https://ncbi.nlm.nih.gov/pubmed/19476645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-94
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