The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury

BACKGROUND: Acute kidney injury frequently accompanies sepsis. Endotoxin is known to reduce tissue levels of cAMP and low levels of cAMP have been associated with renal injury. We, therefore, hypothesized that endotoxin induced renal injury by activating phosphodiesterase 3 (PDE3) which metabolizes...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Choi, Won-Il, Kwon, Kun Young, Seo, Jeong Wook, Beagle, John, Quinn, Deborah A, Hales, Charles A
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2009
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694814/
https://ncbi.nlm.nih.gov/pubmed/19486524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-9-80
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