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The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury
BACKGROUND: Acute kidney injury frequently accompanies sepsis. Endotoxin is known to reduce tissue levels of cAMP and low levels of cAMP have been associated with renal injury. We, therefore, hypothesized that endotoxin induced renal injury by activating phosphodiesterase 3 (PDE3) which metabolizes...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694814/ https://ncbi.nlm.nih.gov/pubmed/19486524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-9-80 |
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