Neuroligin1: a cell adhesion molecule that recruits PSD-95 and NMDA receptors by distinct mechanisms during synaptogenesis

BACKGROUND: The cell adhesion molecule pair neuroligin1 (Nlg1) and β-neurexin (β-NRX) is a powerful inducer of postsynaptic differentiation of glutamatergic synapses in vitro. Because Nlg1 induces accumulation of two essential components of the postsynaptic density (PSD) – PSD-95 and NMDA receptors...

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Main Authors: Barrow, Stephanie L, Constable, John RL, Clark, Eliana, El-Sabeawy, Faten, McAllister, A Kimberley, Washbourne, Philip
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694798/
https://ncbi.nlm.nih.gov/pubmed/19450252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-4-17
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