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Blockade of melanocortin transmission inhibits cocaine reward

Abstract Melanocortins and the melanocortin-4 receptor (MC4-R) are enriched in the nucleus accumbens, a brain region that has been implicated in the rewarding action of cocaine and other drugs of abuse. In the present study we use a number of rat behavioral models to show that infusion of a melanoco...

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Autores principales: Hsu, Richard, Taylor, Jane R., Newton, Samuel S., Alvaro, John D., Haile, Colin, Han, G., Hruby, Victor J., Nestler, Eric J., Duman, Ronald S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694749/
https://ncbi.nlm.nih.gov/pubmed/15869520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2005.04038.x
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