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Isolation of an enhancer from the rat tyrosine hydroxylase promoter that supports long-term, neuronal-specific expression from a neurofilament promoter, in a helper virus-free HSV-1 vector system

Direct gene transfer into neurons, using a virus vector, has been used to study neuronal physiology and learning, and has potential for supporting gene therapy treatments for specific neurological diseases. Many of these applications require high-level, long-term recombinant gene expression, in fore...

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Main Authors: Gao, Qingshen, Sun, Mei, Wang, Xiaodan, Geller, Alfred I.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694737/
https://ncbi.nlm.nih.gov/pubmed/17169349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2006.10.018
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