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Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus

A group of post-natal neurodevelopmental disorders collectively referred to as MeCP2 disorders are caused by aberrations in the gene encoding methyl-CpG-binding protein 2 (MECP2). Loss of MeCP2 function causes Rett syndrome (RTT), whereas increased copy number of the gene causes MECP2 duplication or...

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Bibliographic Details
Main Authors: Ben-Shachar, Shay, Chahrour, Maria, Thaller, Christina, Shaw, Chad A., Zoghbi, Huda Y.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694691/
https://ncbi.nlm.nih.gov/pubmed/19369296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp181
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