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MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription
Mutations in the gene encoding the transcriptional repressor methyl-CpG binding protein 2 (MeCP2) cause the neurodevelopmental disorder Rett syndrome. Loss of function as well as increased dosage of MECP2 gene cause a host of neuropsychiatric disorders. To explore the molecular mechanism(s) underlyi...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443785/ https://ncbi.nlm.nih.gov/pubmed/18511691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1153252 |
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