Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

The molecular complexity of mammalian proteomes demands new methods for mapping the organization of multiprotein complexes. Here, we combine mouse genetics and proteomics to characterize synapse protein complexes and interaction networks. New tandem affinity purification (TAP) tags were fused to the...

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Detalhes bibliográficos
Main Authors: Fernández, Esperanza, Collins, Mark O, Uren, Rachel T, Kopanitsa, Maksym V, Komiyama, Noboru H, Croning, Mike D R, Zografos, Lysimachos, Armstrong, J Douglas, Choudhary, Jyoti S, Grant, Seth G N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694677/
https://ncbi.nlm.nih.gov/pubmed/19455133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.27
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