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Lack of Effect of SU1498, an Inhibitor of Vascular Endothelial Growth Factor Receptor-2, in a Transgenic Murine Model of Retinoblastoma

SU1498, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2), has activity against retinal neovascular diseases. To determine if this drug might have clinical utility against retinoblastoma, we evaluated the effects of SU1498, as well as the expression of VEGFR-2, i...

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Détails bibliographiques
Auteurs principaux: Cebulla, C.M, Jockovich, M.E, Boutrid, H, Piña, Y, Ruggeri, M, Jiao, S, Bhattacharya, S.K, Feuer, W.J, Murray, T.G
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers Ltd. 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694596/
https://ncbi.nlm.nih.gov/pubmed/19517030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874364100802010062
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