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Catalytic, Asymmetric Michael Reactions of Cyclic Diketones with β,γ-Unsaturated-α-ketoesters

[Image: see text] Newly synthesized cinchona alkaloid-derived pyrimidines function as effective asymmetric catalysts for the Michael reaction between cyclic diketones and β,γ-unsaturated-α-ketoesters. The reactions of electrophiles with either aryl or alkyl γ-substituents give 64−99% yields and 94−9...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Calter, Michael A., Wang, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694574/
https://ncbi.nlm.nih.gov/pubmed/19366193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol900586f
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