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Resistance of TNF/LTα double deficient mice to bleomycin-induced fibrosis

In order to evaluate the role and mode of action of TNF in bleomycin-induced lung fibrosis, mice deficient for TNF and LTα (ΔTNF/LTα) were examined at 2 months of age and after 3 weekly i.v. injections of bleomycin. The body weight of the ΔTNF/LTα mice was 88±11% of that of the wild type littermates...

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Bibliografiske detaljer
Main Authors: PIGUET, PIERRE F., KAUFMAN, STEPHEN, BARAZZONE, CONSTANCE, MULLER, MATTHIAS, RYFFEL, BERNHARD, EUGSTER, HANS P.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694518/
https://ncbi.nlm.nih.gov/pubmed/9166104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.1997.d01-240.x
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