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Correction of the TNF-LTα-Deficient Phenotype by Bone Marrow Transplantation
Mice with inactivated TNF-LTα genes have profound abnormalities of the immune system with hypoimmunoglobulinaemia, lack of lymph nodes, undifferentiated spleen, and defective Ig class switch. Transplantation of bone marrow cells from wild-type mice restored the synthesis of TNF, corrected the spleni...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276018/ https://ncbi.nlm.nih.gov/pubmed/9814599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1998/76963 |
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