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Correction of the TNF-LTα-Deficient Phenotype by Bone Marrow Transplantation

Mice with inactivated TNF-LTα genes have profound abnormalities of the immune system with hypoimmunoglobulinaemia, lack of lymph nodes, undifferentiated spleen, and defective Ig class switch. Transplantation of bone marrow cells from wild-type mice restored the synthesis of TNF, corrected the spleni...

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Bibliografische gegevens
Hoofdauteurs: Ryffel, Bernhard, Hir, Michel Le, Müller, Mathias, Eugster, Hans-Pietro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 1998
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276018/
https://ncbi.nlm.nih.gov/pubmed/9814599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1998/76963
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