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Role of Ca(2+)/calmodulin-dependent protein kinase II in dendritic spine remodeling during epileptiform activity in vitro

Epileptiform activity (EA) in vivo and in vitro induces a loss of dendritic spines and synapses. Because CaMKII has been implicated in synaptogenesis and synaptic plasticity, we investigated the role of CaMKII in the effects of EA on spines, using rat hippocampal slice cultures. To visualize dendrit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zha, Xiang-ming, Dailey, Michael E., Green, Steven H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694514/
https://ncbi.nlm.nih.gov/pubmed/19235894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22033
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