Assemblies of calcium/calmodulin-dependent kinase II with actin and their dynamic regulation by calmodulin in dendritic spines

Calcium/calmodulin-dependent kinase II (CaMKII) plays a key role in the plasticity of dendritic spines. Calcium signals cause calcium−calmodulin to activate CaMKII, which leads to remodeling of the actin filament (F-actin) network in the spine. We elucidate the mechanism of the remodeling by combini...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wang, Qian, Chen, Mingchen, Schafer, Nicholas P., Bueno, Carlos, Song, Sarah S., Hudmon, Andy, Wolynes, Peter G., Waxham, M. Neal, Cheung, Margaret S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754556/
https://ncbi.nlm.nih.gov/pubmed/31455737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911452116
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