The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression

Recent genome-wide scans for colorectal cancer (CRC) have revealed the SMAD7 (mothers against decapentaplegic homolog 7) gene as a locus associated with a modest, but highly significant increase in CRC risk. To identify the causal basis of the association between 18q21 variation and CRC, we resequen...

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Detalhes bibliográficos
Main Authors: Pittman, Alan M., Naranjo, Silvia, Webb, Emily, Broderick, Peter, Lips, Esther H., van Wezel, Tom, Morreau, Hans, Sullivan, Kate, Fielding, Sarah, Twiss, Philip, Vijayakrishnan, Jayaram, Casares, Fernando, Qureshi, Mobshra, Gómez-Skarmeta, José Luis, Houlston, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694486/
https://ncbi.nlm.nih.gov/pubmed/19395656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.092668.109
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